Ptgs1 | prostaglandin-endoperoxide synthase 1

GeneMGI:97797Synonyms: Cox-1, cyclooxygenase 1, +3 more

Physiological systems

21 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Digestive/alimentary Hearing/vestibular/ear

19 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



abnormal auditory brainstem response	1 supporting dataset	Ptgs1^em1(IMPC)Mbp	homozygote	Early adult	2.88x10^-6
enlarged cecum	1 supporting dataset	Ptgs1^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
abnormal cecum morphology	1 supporting dataset	Ptgs1^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Ptgs1.

Associated images

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Histopathology

There is no histopathology data found for Ptgs1.

IMPC related publications

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External links

No external links available for Ptgs1.

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*Ptgs1^em1(IMPC)Mbp*	Inter-exon deletion	‌	mouse
*Ptgs1^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell
*Ptgs1^{tm373741(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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