Polb | polymerase (DNA directed), beta

GeneMGI:97740Synonyms: Pol beta, A430088C08Rik

Physiological systems

18 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Adipose tissue Growth/size/body region Hematopoietic system Mortality/aging

14 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



preweaning lethality, complete penetrance	1 supporting dataset	Polb^{tm1a(KOMP)Wtsi}	homozygote	Early adult	N/A ^*
increased lean body mass	2 supporting datasets	Polb^{tm1a(KOMP)Wtsi}	heterozygote	Early adult	1.04x10^-6
increased mean platelet volume	1 supporting dataset	Polb^{tm1a(KOMP)Wtsi}	heterozygote	Early adult	2.85x10^-7
decreased total body fat amount	1 supporting dataset	Polb^{tm1a(KOMP)Wtsi}	heterozygote	Early adult	3.89x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Polb.

Associated images

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Histopathology

There is no histopathology data found for Polb.

IMPC related publications

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External links

No external links available for Polb.

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*Polb^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Polb^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	es cell
*Polb^{tm2e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	es cell

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