Pmch | pro-melanin-concentrating hormone

GeneMGI:97629Synonyms: A230109K23Rik, melanin-concentrating hormone, +1 more

Physiological systems

21 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Growth/size/body region Skeleton Cardiovascular system Renal/urinary system

17 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

0Associated diseases

Expression examined in:73Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



enlarged heart	1 supporting dataset	Pmch^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	N/A ^*
abnormal kidney morphology	1 supporting dataset	Pmch^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	N/A ^*
increased bone mineral content	1 supporting dataset	Pmch^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	3.01x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Pmch.

Associated images

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Histopathology

There is no histopathology data found for Pmch.

IMPC related publications

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External links

No external links available for Pmch.

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*Pmch^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell mouse
*Pmch^{tm1.1(KOMP)Vlcg}*	Reporter-tagged deletion allele (post Cre, with no selection cassette)	‌	mouse
*Pmch^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell

My Genes