Serpinb2 | serine (or cysteine) peptidase inhibitor, clade B, member 2

GeneMGI:97609Synonyms: Planh2, ovalbumin, +1 more

Physiological systems

17 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Homeostasis/metabolism Vision/eye Behavior/neurological Skeleton

13 No significant impact

7 Not tested

Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:48Adult tissues
50Embryo tissues

Phenotypes

increased circulating cholesterol level1 supporting datasetSerpinb2tm1b(EUCOMM)WtsihomozygoteEarly adult8.43x10-5 
increased circulating creatinine level1 supporting datasetSerpinb2tm1b(EUCOMM)WtsihomozygoteEarly adult2.27x10-5 
hyperactivity1 supporting datasetSerpinb2tm1b(EUCOMM)WtsihomozygoteEarly adult9x10-6 
increased circulating HDL cholesterol level1 supporting datasetSerpinb2tm1b(EUCOMM)WtsihomozygoteEarly adult8.66x10-5 
decreased bone mineral content1 supporting datasetSerpinb2tm1b(EUCOMM)WtsihomozygoteEarly adult9.18x10-5 
cataract1 supporting datasetSerpinb2tm1b(EUCOMM)WtsihomozygoteEarly adult1.14x10-7 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Serpinb2tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Serpinb2tm1b(EUCOMM)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Serpinb2tm1e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell
Serpinb2tm387184(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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