Prkcz | protein kinase C, zeta
Physiological systems
21 / 24 physiological systems tested
1 Significantly impacted by the knock-out
Homeostasis/metabolism
20 No significant impact
3 Not tested
Data collections
Gene metrics:8Significant phenotypes
1Associated diseases
Expression examined in:45Adult tissues
0Embryo tissues
| increased circulating alkaline phosphatase level | 1 supporting dataset | Prkcztm1a(EUCOMM)Wtsi | homozygote | Early adult | 2.27x10-10 | ||
| increased circulating alanine transaminase level | 1 supporting dataset | Prkcztm1a(EUCOMM)Wtsi | homozygote | Early adult | 7.45x10-12 | ||
| increased circulating aspartate transaminase level | 1 supporting dataset | Prkcztm1a(EUCOMM)Wtsi | homozygote | Early adult | 1.12x10-10 | ||
| increased circulating LDL cholesterol level | 1 supporting dataset | Prkcztm1a(EUCOMM)Wtsi | homozygote | Early adult | 7.07x10-6 | ||
| increased lactate dehydrogenase level | 1 supporting dataset | Prkcztm1a(EUCOMM)Wtsi | homozygote | Early adult | 1.75x10-15 | ||
| decreased circulating creatinine level | 1 supporting dataset | Prkcztm1a(EUCOMM)Wtsi | heterozygote | Early adult | 7.1x10-5 | ||
| increased circulating iron level | 1 supporting dataset | Prkcztm1a(EUCOMM)Wtsi | heterozygote | Early adult | 2.54x10-6 |
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External links
No external links available for Prkcz.
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| Prkcztm1(EGFP_CreERT2)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | es cell |
| Prkcztm1.1(EGFP_CreERT2)Wtsi | Reporter-tagged deletion allele (post Cre, with no selection cassette) | | es cell |
| Prkcztm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector es cell mouse |
| Prkcztm1e(EUCOMM)Wtsi | Targeted, non-conditional allele | | es cell |