Pkm | pyruvate kinase, muscle

GeneMGI:97591Synonyms: Pk3, Pk-3, +2 more

Physiological systems

14 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Embryo Growth/size/body region Mortality/aging

11 No significant impact

10 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



abnormal embryo size	1 supporting dataset	Pkm^em1(IMPC)Bay	heterozygote	E9.5	N/A ^*
preweaning lethality, complete penetrance	3 supporting datasets	Pkm^em1(IMPC)Bay	homozygote	Early adult	N/A ^*
embryonic growth retardation	1 supporting dataset	Pkm^em1(IMPC)Bay	heterozygote	E9.5	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Pkm.

Associated images

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Histopathology

There is no histopathology data found for Pkm.

IMPC related publications

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External links

No external links available for Pkm.

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*Pkm^em1(IMPC)Bay*	Exon Deletion	‌	mouse
*Pkm^{tm372534(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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