Pde1b | phosphodiesterase 1B, Ca2+-calmodulin dependent

Physiological systems

18 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Hematopoietic system Behavior/neurological

16 No significant impact

6 Not tested

Gene metrics:3Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

hyperactivity1 supporting datasetPde1btm1b(EUCOMM)WtsihomozygoteEarly adult6.9x10-5 
increased mean corpuscular hemoglobin concentration1 supporting datasetPde1btm1b(EUCOMM)WtsihomozygoteEarly adult2.83x10-5 
increased mean corpuscular hemoglobin1 supporting datasetPde1btm1b(EUCOMM)WtsihomozygoteEarly adult2.65x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Pde1btm1(EGFP/cre/ERT2)WtsiReporter-tagged deletion allele (with selection cassette)ES Cell
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Pde1btm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
Pde1btm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
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Pde1btm1b(EUCOMM)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Pde1btm1e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell

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