Cdk17 | cyclin dependent kinase 17

GeneMGI:97517Synonyms: 6430598J10Rik, Pctk2

Physiological systems

19 / 24 physiological systems tested

5 Significantly impacted by the knock-out

 Embryo Growth/size/body region Behavior/neurological Craniofacial Mortality/aging

14 No significant impact

5 Not tested

Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

hyperactivity1 supporting datasetCdk17em1(IMPC)JheterozygoteEarly adult5.05x10-6 
abnormal embryo size1 supporting datasetCdk17em1(IMPC)JhomozygoteE18.5N/A * 
preweaning lethality, incomplete penetrance1 supporting datasetCdk17em1(IMPC)JhomozygoteEarly adultN/A * 
increased vertical activity1 supporting datasetCdk17em1(IMPC)JhomozygoteEarly adult4.83x10-6 
abnormal snout morphology1 supporting datasetCdk17em1(IMPC)JhomozygoteEarly adult7.57x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Cdk17em1(IMPC)JExon Deletionmouse
Cdk17tm1(KOMP)WtsiReporter-tagged deletion allele (with selection cassette)targeting vector
ES Cell
Cdk17tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Cdk17tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell
Cdk17tm2a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell

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