P4hb | prolyl 4-hydroxylase, beta polypeptide
Physiological systems
22 / 24 physiological systems tested
3 Significantly impacted by the knock-out
Embryo Growth/size/body region Mortality/aging
19 No significant impact
2 Not tested
Data collections
Gene metrics:3Significant phenotypes
3Associated diseases
Expression examined in:73Adult tissues
30Embryo tissues
| embryonic growth retardation | 1 supporting dataset | P4hbtm1b(KOMP)Wtsi | homozygote | E9.5 | N/A * | ||
| preweaning lethality, incomplete penetrance | 3 supporting datasets | P4hbtm1b(KOMP)Wtsi | homozygote | Early adult | N/A * | ||
| embryonic lethality prior to tooth bud stage | 1 supporting dataset | P4hbtm1b(KOMP)Wtsi | homozygote | E12.5 | N/A * |
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External links
No external links available for P4hb.
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| P4hbtm119336(L1L2_Bact_P) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |
| P4hbtm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| P4hbtm1b(KOMP)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| P4hbtm1e(KOMP)Wtsi | Targeted, non-conditional allele | | ES Cell |
| P4hbtm2e(EUCOMM)Wtsi | Targeted, non-conditional allele | | ES Cell |