Otc | ornithine transcarbamylase
GeneMGI:97448
Physiological systems
21 / 24 physiological systems tested
4 Significantly impacted by the knock-out
Homeostasis/metabolism Immune system Endocrine/exocrine gland Hematopoietic system
17 No significant impact
3 Not tested
Data collections
Gene metrics:3Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| increased circulating alanine transaminase level | 1 supporting dataset | Otcem1(IMPC)Tcp | heterozygote | Early adult | 1.12x10-9 | ||
| enlarged thymus | 1 supporting dataset | Otcem1(IMPC)Tcp | heterozygote | Early adult | N/A * | ||
| increased circulating triglyceride level | 1 supporting dataset | Otcem1(IMPC)Tcp | heterozygote | Early adult | 2.69x10-5 |
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External links
No external links available for Otc.
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| Otcem1(IMPC)Tcp | Exon Deletion | | mouse |
| Otctm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Otctm1e(KOMP)Wtsi | Targeted, non-conditional allele | | ES Cell |
| Otctm2e(KOMP)Wtsi | Targeted, non-conditional allele | | ES Cell |
| Otctm361391(L1L2_Bact_P) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |
| Otctm3a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Otctm3e(EUCOMM)Wtsi | Targeted, non-conditional allele | | ES Cell |