Oprl1 | opioid receptor-like 1

GeneMGI:97440Synonyms: MOR-C, ORL1, +6 more

Physiological systems

20 / 24 physiological systems tested

6 Significantly impacted by the knock-out

Immune system Integument Growth/size/body region Vision/eye Liver/biliary system Hematopoietic system

14 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:10Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



increased red blood cell distribution width	1 supporting dataset	Oprl1^em1(IMPC)Mbp	homozygote	Early adult	3.71x10^-6
abnormal skin morphology	2 supporting datasets	Oprl1^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
enlarged spleen	1 supporting dataset	Oprl1^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
cataract	1 supporting dataset	Oprl1^em1(IMPC)Mbp	homozygote	Early adult	4.36x10^-6
increased mean platelet volume	1 supporting dataset	Oprl1^em1(IMPC)Mbp	homozygote	Early adult	9.31x10^-6
small liver	1 supporting dataset	Oprl1^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
abnormal vitreous body morphology	1 supporting dataset	Oprl1^em1(IMPC)Mbp	homozygote	Early adult	8.87x10^-5
decreased mean corpuscular hemoglobin	1 supporting dataset	Oprl1^em1(IMPC)Mbp	homozygote	Early adult	3.02x10^-19
abnormal eye morphology	1 supporting dataset	Oprl1^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
microphthalmia	1 supporting dataset	Oprl1^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Oprl1.

Associated images

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Histopathology

There is no histopathology data found for Oprl1.

IMPC related publications

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External links

No external links available for Oprl1.

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*Oprl1^em1(IMPC)Mbp*	Intra-exon deletion	‌	mouse
*Oprl1^{tm1(NCOM)Mfgc}*	Reporter-tagged deletion allele (with selection cassette)	‌	targeting vector ES Cell
*Oprl1^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Oprl1^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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