Slc10a1 | solute carrier family 10 (sodium/bile acid cotransporter family), member 1

GeneMGI:97379Synonyms: sodium bile acid cotransporting polypeptide, Ntcp

Physiological systems

20 / 24 physiological systems tested

6 Significantly impacted by the knock-out

 Reproductive system Endocrine/exocrine gland Integument Growth/size/body region Vision/eye Liver/biliary system

14 No significant impact

4 Not tested

Gene metrics:9Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal gallbladder morphology1 supporting datasetSlc10a1em1(IMPC)MbphomozygoteEarly adultN/A * 
abnormal skin morphology1 supporting datasetSlc10a1em1(IMPC)MbphomozygoteEarly adultN/A * 
abnormal seminal vesicle morphology1 supporting datasetSlc10a1em1(IMPC)MbphomozygoteEarly adultN/A * 
abnormal vitreous body morphology1 supporting datasetSlc10a1em1(IMPC)MbphomozygoteEarly adult5.99x10-5 
enlarged gallbladder1 supporting datasetSlc10a1em1(IMPC)MbphomozygoteEarly adultN/A * 
cataract1 supporting datasetSlc10a1em1(IMPC)MbphomozygoteEarly adult6.35x10-5 
abnormal liver morphology1 supporting datasetSlc10a1em1(IMPC)MbphomozygoteEarly adultN/A * 
small seminal vesicle1 supporting datasetSlc10a1em1(IMPC)MbphomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Slc10a1em1(IMPC)MbpExon Deletionmouse

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