Msn | moesin

GeneMGI:97167

Physiological systems

17 / 24 physiological systems tested

6 Significantly impacted by the knock-out

Immune system Growth/size/body region Vision/eye Hematopoietic system Behavior/neurological Cardiovascular system

11 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:9Significant phenotypes

2Associated diseases

Expression examined in:97Adult tissues

50Embryo tissues

Phenotypes

Zygosity:

Phy. System:



increased mean corpuscular hemoglobin	1 supporting dataset	Msn^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	2.02x10^-11
decreased erythrocyte cell number	1 supporting dataset	Msn^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	0
decreased erythrocyte cell number	1 supporting dataset	Msn^{tm1b(EUCOMM)Hmgu}	hemizygote	Early adult	6.05x10^-10
decreased hematocrit	1 supporting dataset	Msn^{tm1b(EUCOMM)Hmgu}	hemizygote	Early adult	4.11x10^-9
decreased hemoglobin content	1 supporting dataset	Msn^{tm1b(EUCOMM)Hmgu}	hemizygote	Early adult	3.28x10^-5
increased mean corpuscular volume	1 supporting dataset	Msn^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	3.85x10^-7
decreased leukocyte cell number	1 supporting dataset	Msn^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	2.22x10^-16
decreased hemoglobin content	1 supporting dataset	Msn^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	3.61x10^-13
impaired pupillary reflex	1 supporting dataset	Msn^{tm1b(EUCOMM)Hmgu}	hemizygote	Early adult	7.29x10^-7
increased heart weight	1 supporting dataset	Msn^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	8.8x10^-9

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Msn.

Associated images

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Histopathology

There is no histopathology data found for Msn.

IMPC related publications

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External links

No external links available for Msn.

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*Msn^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Msn^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Msn^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell
*Msn^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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