Mov10 | Mov10 RISC complex RNA helicase

GeneMGI:97054Synonyms: Mov-10

Physiological systems

17 / 24 physiological systems tested

5 Significantly impacted by the knock-out

 Integument Nervous system Vision/eye Behavior/neurological Cardiovascular system

12 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal retina morphology1 supporting datasetMov10em1(IMPC)TcphomozygoteEarly adult2.11x10-5 
increased freezing behavior1 supporting datasetMov10em1(IMPC)TcphomozygoteEarly adult1.9x10-5 
decreased prepulse inhibition2 supporting datasetsMov10em1(IMPC)TcphomozygoteEarly adult1.7x10-6 
abnormal retina vasculature morphology1 supporting datasetMov10em1(IMPC)TcphomozygoteEarly adult1.93x10-5 
abnormal retina blood vessel morphology1 supporting datasetMov10em1(IMPC)TcphomozygoteEarly adult7.21x10-5 
abnormal skin morphology1 supporting datasetMov10em1(IMPC)TcphomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Mov10em1(IMPC)TcpExon Deletionmouse
Mov10tm1(KOMP)MbpReporter-tagged deletion allele (with selection cassette)targeting vector
ES Cell
Mov10tm456285(L1L2_GT2_LF2A_LacZ_BetactP_neo)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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