Me1 | malic enzyme 1, NADP(+)-dependent, cytosolic

GeneMGI:97043Synonyms: Mod-1, D9Ertd267e, +2 more

Physiological systems

17 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Homeostasis/metabolism Immune system Nervous system

14 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



enlarged lymph nodes	1 supporting dataset	Me1^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*
improved glucose tolerance	1 supporting dataset	Me1^em1(IMPC)Tcp	homozygote	Early adult	2.26x10^-5
increased circulating alkaline phosphatase level	1 supporting dataset	Me1^em1(IMPC)Tcp	homozygote	Early adult	1.55x10^-6
decreased prepulse inhibition	1 supporting dataset	Me1^em1(IMPC)Tcp	homozygote	Early adult	8.71x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Me1.

Associated images

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Histopathology

There is no histopathology data found for Me1.

IMPC related publications

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External links

No external links available for Me1.

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*Me1^em1(IMPC)Tcp*	Exon Deletion	‌	mouse
*Me1^{tm1(NCOM)Mfgc}*	Reporter-tagged deletion allele (with selection cassette)	‌	targeting vector ES Cell
*Me1^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell

My Genes