Golga3 | golgin A3

GeneMGI:96958Synonyms: Mea2, G1-499-14, +3 more

Physiological systems

19 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Homeostasis/metabolism Reproductive system Hematopoietic system

16 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:6Significant phenotypes

0Associated diseases

Expression examined in:46Adult tissues

42Embryo tissues

Phenotypes

Phy. System:



male infertility	1 supporting dataset	Golga3^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	N/A ^*
impaired glucose tolerance	1 supporting dataset	Golga3^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	2.88x10^-5
increased circulating alanine transaminase level	1 supporting dataset	Golga3^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	1.39x10^-5
increased circulating alkaline phosphatase level	1 supporting dataset	Golga3^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	1.42x10^-16
decreased hemoglobin content	1 supporting dataset	Golga3^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	7.62x10^-6
increased circulating aspartate transaminase level	1 supporting dataset	Golga3^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	4.25x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Golga3.

Associated images

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Histopathology

There is no histopathology data found for Golga3.

IMPC related publications

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External links

No external links available for Golga3.

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*Golga3^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Golga3^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Golga3^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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