Ky | kyphoscoliosis peptidase

GeneMGI:96709Synonyms: D9Mgc44e

Physiological systems

17 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Homeostasis/metabolism Immune system Hematopoietic system Behavior/neurological

13 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:9Significant phenotypes
3Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased circulating glucose level1 supporting datasetKyem1(IMPC)JheterozygoteEarly adult3.82x10-6 
decreased exploration in new environment1 supporting datasetKyem1(IMPC)JhomozygoteEarly adult2.17x10-11 
impaired righting response1 supporting datasetKyem1(IMPC)JhomozygoteEarly adult3.83x10-6 
abnormal behavior1 supporting datasetKyem1(IMPC)JhomozygoteEarly adult1.65x10-18 
increased grip strength2 supporting datasetsKyem1(IMPC)JhomozygoteEarly adult1.28x10-10 
abnormal gait1 supporting datasetKyem1(IMPC)JhomozygoteEarly adult1.83x10-19 
tremors1 supporting datasetKyem1(IMPC)JhomozygoteEarly adult9.52x10-10 
decreased grip strength1 supporting datasetKyem1(IMPC)JhomozygoteEarly adult2.43x10-5 
increased leukocyte cell number1 supporting datasetKyem1(IMPC)JheterozygoteEarly adult1.11x10-7 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Kyem1(IMPC)JExon Deletionmouse

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