Krt5 | keratin 5

GeneMGI:96702Synonyms: Krt2-5, 3300001P10Rik, +2 more

Physiological systems

22 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Immune system Mortality/aging

20 No significant impact

2 Not tested

Gene metrics:3Significant phenotypes
13Associated diseases
Expression examined in:73Adult tissues
50Embryo tissues

Phenotypes

preweaning lethality, incomplete penetrance2 supporting datasetsKrt5tm1.1(KOMP)VlcghomozygoteEarly adultN/A * 
preweaning lethality, complete penetrance1 supporting datasetKrt5tm1.1(KOMP)VlcghomozygoteEarly adultN/A * 
abnormal lymph node morphology1 supporting datasetKrt5tm1.1(KOMP)VlcgheterozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Krt5em1(IMPC)WtsiPoint Mutationmouse
Krt5tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
mouse
Krt5tm1(NCOM)MfgcReporter-tagged deletion allele (with selection cassette)targeting vector
ES Cell
Krt5tm1.1(KOMP)VlcgReporter-tagged deletion allele (post Cre, with no selection cassette)mouse

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