Ipp | IAP promoted placental gene

GeneMGI:96581Synonyms: Mipp, D4Jhu8

Physiological systems

18 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Homeostasis/metabolism Immune system Hematopoietic system Behavior/neurological

14 No significant impact

6 Not tested

Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:48Adult tissues
50Embryo tissues

Phenotypes

impaired righting response1 supporting datasetIpptm1.1(KOMP)VlcghomozygoteEarly adult1.77x10-5 
decreased leukocyte cell number1 supporting datasetIpptm1.1(KOMP)VlcghomozygoteEarly adult3.12x10-7 
abnormal sleep behavior1 supporting datasetIpptm1.1(KOMP)VlcghomozygoteEarly adult2.92x10-6 
decreased circulating glucose level1 supporting datasetIpptm1.1(KOMP)VlcghomozygoteEarly adult4.96x10-5 
decreased circulating chloride level1 supporting datasetIpptm1.1(KOMP)VlcghomozygoteEarly adult2.25x10-5 
increased circulating alkaline phosphatase level1 supporting datasetIpptm1.1(KOMP)VlcghomozygoteEarly adult4.1x10-18 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Ipptm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
mouse
Ipptm1.1(KOMP)VlcgReporter-tagged deletion allele (post Cre, with no selection cassette)mouse
Ipptm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Ipptm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell
Ipptm222154(L1L2_Bact_P)Reporter-tagged deletion allele (with selection cassette)targeting vector

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