Inhbb | inhibin beta-B

GeneMGI:96571Synonyms: activin beta-B

Physiological systems

17 / 24 physiological systems tested

6 Significantly impacted by the knock-out

Homeostasis/metabolism Nervous system Vision/eye Hematopoietic system Behavior/neurological Cardiovascular system

11 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:16Significant phenotypes

0Associated diseases

Expression examined in:46Adult tissues

42Embryo tissues

Phenotypes

Phy. System:



decreased erythrocyte cell number	1 supporting dataset	Inhbb^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	5.25x10^-5
hyperactivity	6 supporting datasets	Inhbb^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	9.99x10^-10
increased circulating creatinine level	1 supporting dataset	Inhbb^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	3.14x10^-5
cornea opacity	1 supporting dataset	Inhbb^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	7.09x10^-19
cornea vascularization	1 supporting dataset	Inhbb^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	1.11x10^-11
narrow eye opening	1 supporting dataset	Inhbb^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	9.54x10^-5
abnormal locomotor behavior	1 supporting dataset	Inhbb^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	4.75x10^-9
abnormal gait	1 supporting dataset	Inhbb^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	5.99x10^-11
increased circulating bilirubin level	1 supporting dataset	Inhbb^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	1.48x10^-35
abnormal eye morphology	1 supporting dataset	Inhbb^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

Download data as:

Rows per page:

‌



‌	‌	‌	‌	‌	‌	‌	‌	‌	‌

* This parameter was manually assessed for significance.

Download data as:

lacZ Expression

No adult expression data available for Inhbb.

Associated images

Loading...

Histopathology

There is no histopathology data found for Inhbb.

IMPC related publications

Loading...

External links

No external links available for Inhbb.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.



*Inhbb^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell
*Inhbb^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Inhbb^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Inhbb^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

My Genes