Il1a | interleukin 1 alpha

GeneMGI:96542Synonyms: Il-1a

Physiological systems

17 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Homeostasis/metabolism Vision/eye Hematopoietic system Behavior/neurological

13 No significant impact

7 Not tested

Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:48Adult tissues
25Embryo tissues

Phenotypes

decreased hemoglobin content1 supporting datasetIl1atm1b(EUCOMM)WtsihomozygoteEarly adult6.58x10-6 
increased startle reflex1 supporting datasetIl1atm1b(EUCOMM)WtsihomozygoteEarly adult8.85x10-7 
decreased circulating serum albumin level1 supporting datasetIl1atm1b(EUCOMM)WtsihomozygoteEarly adult4.68x10-5 
decreased erythrocyte cell number1 supporting datasetIl1atm1b(EUCOMM)WtsihomozygoteEarly adult2.99x10-6 
cataract1 supporting datasetIl1atm1b(EUCOMM)WtsihomozygoteEarly adult9.84x10-5 
decreased hematocrit1 supporting datasetIl1atm1b(EUCOMM)WtsihomozygoteEarly adult1.07x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Il1atm1(NCOM)CmhdReporter-tagged deletion allele (with selection cassette)targeting vector
ES Cell
Il1atm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Il1atm1b(EUCOMM)WtsiReporter-tagged deletion allele (with selection cassette)mouse

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