Il1a | interleukin 1 alpha
Physiological systems
17 / 24 physiological systems tested
4 Significantly impacted by the knock-out
Homeostasis/metabolism Vision/eye Hematopoietic system Behavior/neurological
13 No significant impact
7 Not tested
Data collections
Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:48Adult tissues
25Embryo tissues
decreased hemoglobin content | 1 supporting dataset | Il1atm1b(EUCOMM)Wtsi | homozygote | Early adult | 6.58x10-6 | ||
increased startle reflex | 1 supporting dataset | Il1atm1b(EUCOMM)Wtsi | homozygote | Early adult | 8.85x10-7 | ||
decreased circulating serum albumin level | 1 supporting dataset | Il1atm1b(EUCOMM)Wtsi | homozygote | Early adult | 4.68x10-5 | ||
decreased erythrocyte cell number | 1 supporting dataset | Il1atm1b(EUCOMM)Wtsi | homozygote | Early adult | 2.99x10-6 | ||
cataract | 1 supporting dataset | Il1atm1b(EUCOMM)Wtsi | homozygote | Early adult | 9.84x10-5 | ||
decreased hematocrit | 1 supporting dataset | Il1atm1b(EUCOMM)Wtsi | homozygote | Early adult | 1.07x10-5 |
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External links
No external links available for Il1a.
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Il1atm1(NCOM)Cmhd | Reporter-tagged deletion allele (with selection cassette) | | targeting vector ES Cell |
Il1atm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
Il1atm1b(EUCOMM)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | mouse |