Hoxc12 | homeobox C12

GeneMGI:96194Synonyms: Hox-3.8

Physiological systems

18 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Homeostasis/metabolism Limbs/digits/tail Behavior/neurological

15 No significant impact

6 Not tested

Gene metrics:3Significant phenotypes
0Associated diseases
Expression examined in:48Adult tissues
46Embryo tissues

Phenotypes

abnormal tail length2 supporting datasetsHoxc12tm1.1(KOMP)VlcghomozygoteEarly adult4.06x10-20 
decreased fasting circulating glucose level1 supporting datasetHoxc12tm1.1(KOMP)VlcghomozygoteEarly adult1.54x10-6 
tremors1 supporting datasetHoxc12tm1.1(KOMP)VlcghomozygoteEarly adult9.17x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Hoxc12tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
mouse
Hoxc12tm1.1(KOMP)VlcgReporter-tagged deletion allele (post Cre, with no selection cassette)mouse
Hoxc12tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Hoxc12tm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell
Hoxc12tm370742(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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