Hmgn1 | high mobility group nucleosomal binding domain 1

GeneMGI:96120Synonyms: Hmg14, HMG-14

Physiological systems

19 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Homeostasis/metabolism Adipose tissue Growth/size/body region Behavior/neurological

15 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased circulating creatinine level1 supporting datasetHmgn1em1(IMPC)IcshomozygoteEarly adult8.2x10-5 
decreased lean body mass1 supporting datasetHmgn1em1(IMPC)IcshomozygoteEarly adult9.7x10-5 
decreased food intake1 supporting datasetHmgn1em1(IMPC)IcshomozygoteEarly adult1.37x10-6 
increased total body fat amount1 supporting datasetHmgn1em1(IMPC)IcshomozygoteEarly adult2.14x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Hmgn1em1(IMPC)IcsDeletionmouse
Hmgn1em2(IMPC)IcsDeletionmouse
Hmgn1tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
Hmgn1tm1e(EUCOMM)HmguTargeted, non-conditional allelees cell

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