Hivep1 | human immunodeficiency virus type I enhancer binding protein 1

GeneMGI:96100Synonyms: Cryabp1, alphaA-CRYBP1

Physiological systems

21 / 24 physiological systems tested

7 Significantly impacted by the knock-out

Homeostasis/metabolism Immune system Growth/size/body region Nervous system Hematopoietic system Cardiovascular system Mortality/aging

14 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:6Significant phenotypes

0Associated diseases

Expression examined in:42Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



increased heart weight	2 supporting datasets	Hivep1^tm1(KOMP)Mbp	heterozygote	Early adult	1.41x10^-6
preweaning lethality, incomplete penetrance	1 supporting dataset	Hivep1^tm1(KOMP)Mbp	homozygote	Early adult	N/A ^*
increased circulating aspartate transaminase level	1 supporting dataset	Hivep1^tm1(KOMP)Mbp	heterozygote	Early adult	2.49x10^-10
increased circulating alanine transaminase level	1 supporting dataset	Hivep1^tm1(KOMP)Mbp	heterozygote	Early adult	7.04x10^-42
increased basophil cell number	1 supporting dataset	Hivep1^tm1(KOMP)Mbp	heterozygote	Early adult	3.76x10^-5
decreased prepulse inhibition	1 supporting dataset	Hivep1^tm1(KOMP)Mbp	heterozygote	Early adult	4.61x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Hivep1.

Associated images

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Histopathology

There is no histopathology data found for Hivep1.

IMPC related publications

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External links

No external links available for Hivep1.

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*Hivep1^tm1(KOMP)Mbp*	Reporter-tagged deletion allele (with selection cassette)	‌	targeting vector ES Cell mouse
*Hivep1^{tm1.1(KOMP)Mbp}*	Reporter-tagged deletion allele (post Cre, with no selection cassette)	‌	mouse

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