Hbb-bh2 | hemoglobin beta, bh2

GeneMGI:96025Synonyms: Gm5736

Physiological systems

17 / 24 physiological systems tested

1 Significantly impacted by the knock-out

 Hematopoietic system

16 No significant impact

7 Not tested

Gene metrics:2Significant phenotypes
29Associated diseases
Expression examined in:152Adult tissues
50Embryo tissues

Phenotypes

decreased mean corpuscular hemoglobin1 supporting datasetHbb-bh2tm1b(EUCOMM)HmguhomozygoteEarly adult1.52x10-10 
increased red blood cell distribution width1 supporting datasetHbb-bh2tm1b(EUCOMM)HmguhomozygoteEarly adult1.59x10-20 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Hbb-bh2tm1(KOMP)MbpReporter-tagged deletion allele (with selection cassette)targeting vector
ES Cell
Hbb-bh2tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Hbb-bh2tm1b(EUCOMM)HmguReporter-tagged deletion allele (with selection cassette)mouse
Hbb-bh2tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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