H2-M5 | histocompatibility 2, M region locus 5

GeneMGI:95917Synonyms: H-2M5, CRW2, +1 more

Physiological systems

19 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Homeostasis/metabolism Growth/size/body region Cardiovascular system

16 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

12Associated diseases

Expression examined in:45Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



increased heart weight	1 supporting dataset	H2-M5^{tm1(KOMP)Wtsi}	homozygote	Early adult	5.2x10^-5
increased lean body mass	1 supporting dataset	H2-M5^{tm1(KOMP)Wtsi}	homozygote	Early adult	1.01x10^-5
decreased circulating alkaline phosphatase level	1 supporting dataset	H2-M5^{tm1(KOMP)Wtsi}	homozygote	Early adult	7.15x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for H2-M5.

Associated images

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Histopathology

There is no histopathology data found for H2-M5.

IMPC related publications

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External links

No external links available for H2-M5.

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*H2-M5^tm1(KOMP)Mbp*	Reporter-tagged deletion allele (with selection cassette)	‌	targeting vector es cell
*H2-M5^{tm1(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	targeting vector es cell mouse

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