Pfdn6 | prefoldin subunit 6

GeneMGI:95908Synonyms: H-2Ke2, Ke-2, +1 more

Physiological systems

18 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Homeostasis/metabolism Hematopoietic system Behavior/neurological Mortality/aging

14 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:5Significant phenotypes

0Associated diseases

Expression examined in:48Adult tissues

25Embryo tissues

Phenotypes

Zygosity:

Phy. System:



preweaning lethality, incomplete penetrance	1 supporting dataset	Pfdn6^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	N/A ^*
decreased circulating glucose level	1 supporting dataset	Pfdn6^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	3.1x10^-6
decreased mean corpuscular hemoglobin concentration	1 supporting dataset	Pfdn6^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	1.78x10^-7
increased mean corpuscular volume	1 supporting dataset	Pfdn6^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	1.18x10^-8
impaired righting response	1 supporting dataset	Pfdn6^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	4.53x10^-10

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Pfdn6.

Associated images

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Histopathology

There is no histopathology data found for Pfdn6.

IMPC related publications

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External links

No external links available for Pfdn6.

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*Pfdn6^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell mouse
*Pfdn6^{tm1(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	targeting vector ES Cell
*Pfdn6^{tm1.1(KOMP)Vlcg}*	Reporter-tagged deletion allele (post Cre, with no selection cassette)	‌	mouse

My Genes