Grik3 | glutamate receptor, ionotropic, kainate 3

GeneMGI:95816Synonyms: Glur7, Glur-7

Physiological systems

20 / 24 physiological systems tested

8 Significantly impacted by the knock-out

Homeostasis/metabolism Immune system Integument Growth/size/body region Vision/eye Hematopoietic system Behavior/neurological Renal/urinary system

12 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:12Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



abnormal skin morphology	1 supporting dataset	Grik3^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
abnormal kidney morphology	1 supporting dataset	Grik3^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
decreased thigmotaxis	2 supporting datasets	Grik3^em1(IMPC)Mbp	homozygote	Early adult	1.09x10^-6
abnormal behavior	1 supporting dataset	Grik3^em1(IMPC)Mbp	homozygote	Early adult	1.19x10^-6
hyperactivity	1 supporting dataset	Grik3^em1(IMPC)Mbp	homozygote	Early adult	3.04x10^-6
increased fasting circulating glucose level	1 supporting dataset	Grik3^em1(IMPC)Mbp	homozygote	Early adult	5.77x10^-7
small kidney	1 supporting dataset	Grik3^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
decreased anxiety-related response	1 supporting dataset	Grik3^em1(IMPC)Mbp	homozygote	Early adult	4.94x10^-7
cataract	1 supporting dataset	Grik3^em1(IMPC)Mbp	homozygote	Early adult	2.2x10^-6
decreased body length	1 supporting dataset	Grik3^em1(IMPC)Mbp	homozygote	Early adult	7.9x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Grik3.

Associated images

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Histopathology

There is no histopathology data found for Grik3.

IMPC related publications

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External links

No external links available for Grik3.

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*Grik3^em1(IMPC)Mbp*	Exon Deletion	‌	mouse
*Grik3^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Grik3^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell
*Grik3^{tm491(L1L2_gt1)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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