Hagh | hydroxyacyl glutathione hydrolase

GeneMGI:95745Synonyms: Rsp29, Glo2, +1 more

Physiological systems

17 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Vision/eye Hematopoietic system Skeleton

14 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:6Significant phenotypes
1Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased red blood cell distribution width1 supporting datasetHaghem1(IMPC)TcphomozygoteEarly adult5.89x10-7 
decreased mean corpuscular volume1 supporting datasetHaghem1(IMPC)TcphomozygoteEarly adult9.3x10-6 
cataract1 supporting datasetHaghem1(IMPC)TcphomozygoteEarly adult2.21x10-7 
abnormal lens morphology1 supporting datasetHaghem1(IMPC)TcphomozygoteEarly adult1.44x10-7 
decreased hematocrit1 supporting datasetHaghem1(IMPC)TcphomozygoteEarly adult5.51x10-5 
abnormal sternum morphology1 supporting datasetHaghem1(IMPC)TcphomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Haghem1(IMPC)TcpExon Deletionmouse
Haghtm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell
Haghtm44797(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector
Haghtm44797(L1L2_gt2)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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