Gh | growth hormone
GeneMGI:95707
Physiological systems
21 / 24 physiological systems tested
12 Significantly impacted by the knock-out
Homeostasis/metabolism Reproductive system Immune system Adipose tissue Growth/size/body region Nervous system Hematopoietic system Behavior/neurological Skeleton Cardiovascular system Mortality/aging Renal/urinary system
9 No significant impact
3 Not tested
Data collections
Gene metrics:24Significant phenotypes
8Associated diseases
Expression examined in:73Adult tissues
0Embryo tissues
| decreased fasting circulating glucose level | 1 supporting dataset | Ghtm1.1(KOMP)Vlcg | homozygote | Early adult | 5.27x10-6 | ||
| decreased lean body mass | 2 supporting datasets | Ghtm1.1(KOMP)Vlcg | homozygote | Early adult | 6.17x10-31 | ||
| decreased bone mineral content | 2 supporting datasets | Ghtm1.1(KOMP)Vlcg | homozygote | Early adult | 7.37x10-39 | ||
| preweaning lethality, incomplete penetrance | 3 supporting datasets | Ghtm1.1(KOMP)Vlcg | homozygote | Early adult | N/A * | ||
| decreased heart weight | 2 supporting datasets | Ghtm1.1(KOMP)Vlcg | homozygote | Early adult | 2.49x10-16 | ||
| increased total body fat amount | 2 supporting datasets | Ghtm1.1(KOMP)Vlcg | homozygote | Early adult | 1.07x10-29 | ||
| small heart | 2 supporting datasets | Ghtm1.1(KOMP)Vlcg | homozygote | Early adult | N/A * | ||
| decreased kidney weight | 2 supporting datasets | Ghtm1.1(KOMP)Vlcg | homozygote | Early adult | 0 | ||
| abnormal kidney morphology | 2 supporting datasets | Ghtm1.1(KOMP)Vlcg | homozygote | Early adult | N/A * | ||
| thrombocytopenia | 1 supporting dataset | Ghtm1.1(KOMP)Vlcg | homozygote | Early adult | 3.66x10-5 |
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External links
No external links available for Gh.
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