Gdf10 | growth differentiation factor 10

GeneMGI:95684Synonyms: Bmp3b

Physiological systems

21 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Homeostasis/metabolism Growth/size/body region Behavior/neurological Renal/urinary system

17 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

0Associated diseases

Expression examined in:73Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



enlarged kidney	1 supporting dataset	Gdf10^{tm2b(KOMP)Wtsi}	homozygote	Early adult	N/A ^*
decreased locomotor activity	1 supporting dataset	Gdf10^{tm2b(KOMP)Wtsi}	homozygote	Early adult	8.65x10^-5
abnormal kidney morphology	1 supporting dataset	Gdf10^{tm2b(KOMP)Wtsi}	homozygote	Early adult	N/A ^*
increased circulating bilirubin level	1 supporting dataset	Gdf10^{tm2b(KOMP)Wtsi}	homozygote	Early adult	2.09x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Gdf10.

Associated images

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Histopathology

There is no histopathology data found for Gdf10.

IMPC related publications

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External links

No external links available for Gdf10.

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*Gdf10^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Gdf10^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell
*Gdf10^{tm2a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Gdf10^{tm2b(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Gdf10^{tm2e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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