Gapdh | glyceraldehyde-3-phosphate dehydrogenase
Physiological systems
22 / 24 physiological systems tested
5 Significantly impacted by the knock-out
Embryo Growth/size/body region Vision/eye Mortality/aging Cardiovascular system
17 No significant impact
2 Not tested
Data collections
Gene metrics:7Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| embryonic growth retardation | 1 supporting dataset | Gapdhem1(IMPC)Mbp | heterozygote | E15.5 | N/A * | ||
| abnormal vitreous body morphology | 1 supporting dataset | Gapdhem1(IMPC)Mbp | heterozygote | Early adult | 5.99x10-5 | ||
| abnormal blood vessel morphology | 1 supporting dataset | Gapdhem1(IMPC)Mbp | heterozygote | E15.5 | N/A * | ||
| embryonic lethality prior to organogenesis | 1 supporting dataset | Gapdhem1(IMPC)Mbp | homozygote | E9.5 | N/A * | ||
| preweaning lethality, complete penetrance | 1 supporting dataset | Gapdhem1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| cataract | 1 supporting dataset | Gapdhem1(IMPC)Mbp | heterozygote | Early adult | 6.35x10-5 | ||
| abnormal retina morphology | 1 supporting dataset | Gapdhem1(IMPC)Mbp | heterozygote | Early adult | 1.86x10-6 |
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External links
No external links available for Gapdh.
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| Gapdhem1(IMPC)Mbp | Whole-gene deletion | | mouse |
| Gapdhtm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Gapdhtm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |