Fgf3 | fibroblast growth factor 3
Physiological systems
21 / 24 physiological systems tested
6 Significantly impacted by the knock-out
Immune system Embryo Growth/size/body region Limbs/digits/tail Behavior/neurological Mortality/aging
15 No significant impact
3 Not tested
Gene metrics:6Significant phenotypes
4Associated diseases
Expression examined in:51Adult tissues
0Embryo tissues
| no spontaneous movement | 1 supporting dataset | Fgf3tm4b(EUCOMM)Hmgu | homozygote | E18.5 | N/A * | ||
| preweaning lethality, complete penetrance | 3 supporting datasets | Fgf3tm4b(EUCOMM)Hmgu | homozygote | Early adult | N/A * | ||
| abnormal embryo size | 1 supporting dataset | Fgf3tm4b(EUCOMM)Hmgu | homozygote | E18.5 | N/A * | ||
| unresponsive to tactile stimuli | 1 supporting dataset | Fgf3tm4b(EUCOMM)Hmgu | homozygote | E18.5 | N/A * | ||
| abnormal embryo size | 1 supporting dataset | Fgf3tm4b(EUCOMM)Hmgu | homozygote | E12.5 | N/A * | ||
| abnormal tail morphology | 2 supporting datasets | Fgf3tm4b(EUCOMM)Hmgu | homozygote | E18.5 | N/A * | ||
| unresponsive to tactile stimuli | 1 supporting dataset | Fgf3tm4b(EUCOMM)Hmgu | heterozygote | E18.5 | N/A * | ||
| enlarged lymph nodes | 1 supporting dataset | Fgf3tm4b(EUCOMM)Hmgu | heterozygote | Early adult | N/A * | ||
| abnormal tail morphology | 1 supporting dataset | Fgf3tm4b(EUCOMM)Hmgu | homozygote | E12.5 | N/A * |
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External links
No external links available for Fgf3.
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| Fgf3tm4a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Fgf3tm4b(EUCOMM)Hmgu | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Fgf3tm4e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |