Smarcad1 | SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1

GeneMGI:95453Synonyms: D6Pas1, Etl1

Physiological systems

19 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Embryo Growth/size/body region Behavior/neurological Mortality/aging

15 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

6Associated diseases

Expression examined in:51Adult tissues

62Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



hyperactivity	1 supporting dataset	Smarcad1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	1.87x10^-5
unresponsive to tactile stimuli	1 supporting dataset	Smarcad1^{tm1b(EUCOMM)Hmgu}	homozygote	E18.5	N/A ^*
unresponsive to tactile stimuli	1 supporting dataset	Smarcad1^{tm1b(EUCOMM)Hmgu}	heterozygote	E18.5	N/A ^*
preweaning lethality, incomplete penetrance	2 supporting datasets	Smarcad1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	N/A ^*
abnormal embryo size	1 supporting dataset	Smarcad1^{tm1b(EUCOMM)Hmgu}	homozygote	E18.5	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Smarcad1.

Associated images

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Histopathology

There is no histopathology data found for Smarcad1.

IMPC related publications

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External links

No external links available for Smarcad1.

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*Smarcad1^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Smarcad1^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Smarcad1^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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