Erg | ETS transcription factor
Physiological systems
21 / 24 physiological systems tested
6 Significantly impacted by the knock-out
Immune system Integument Vision/eye Hematopoietic system Mortality/aging Cardiovascular system
15 No significant impact
3 Not tested
Data collections
Gene metrics:8Significant phenotypes
3Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| prenatal lethality prior to heart atrial septation | 1 supporting dataset | Ergem1(IMPC)Bay | homozygote | E15.5 | N/A * | ||
| preweaning lethality, complete penetrance | 3 supporting datasets | Ergem1(IMPC)Bay | homozygote | Early adult | N/A * | ||
| abnormal spleen morphology | 1 supporting dataset | Ergem1(IMPC)Bay | heterozygote | Early adult | N/A * | ||
| thick ventricular wall | 2 supporting datasets | Ergem1(IMPC)Bay | heterozygote | Early adult | 8.51x10-9 | ||
| decreased leukocyte cell number | 1 supporting dataset | Ergem1(IMPC)Bay | heterozygote | Early adult | 2.3x10-7 | ||
| abnormal coat appearance | 1 supporting dataset | Ergem1(IMPC)Bay | heterozygote | Early adult | 4.2x10-5 | ||
| abnormal eye posterior chamber depth | 1 supporting dataset | Ergem1(IMPC)Bay | heterozygote | Early adult | 9.32x10-5 | ||
| increased heart left ventricle size | 1 supporting dataset | Ergem1(IMPC)Bay | heterozygote | Early adult | 4.18x10-9 |
| | | | | | | | | | |
External links
No external links available for Erg.
All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.
| Ergem1(IMPC)Bay | Exon Deletion | | mouse |
| Ergtm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |