Ercc2 | excision repair cross-complementing rodent repair deficiency, complementation group 2

GeneMGI:95413Synonyms: XPD, Mhdarco15, +2 more

Physiological systems

20 / 24 physiological systems tested

1 Significantly impacted by the knock-out

 Mortality/aging

19 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Viability data
Body weight measurements
Embryo imaging data
Gene metrics:1Significant phenotypes
7Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

preweaning lethality, complete penetrance1 supporting datasetErcc2tm1a(EUCOMM)WtsihomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Ercc2tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Ercc2tm1e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell
Ercc2tm47198(L1L2_gt1)KO first allele (reporter-tagged insertion with conditional potential)targeting vector
Ercc2tm47198(L1L2_gt2)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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