Epb41 | erythrocyte membrane protein band 4.1

GeneMGI:95401Synonyms: Elp-1, Elp1, +3 more

Physiological systems

20 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Hematopoietic system Mortality/aging

18 No significant impact

4 Not tested

Gene metrics:3Significant phenotypes
2Associated diseases
Expression examined in:48Adult tissues
25Embryo tissues

Phenotypes

decreased mean corpuscular volume1 supporting datasetEpb41tm1b(KOMP)MbpheterozygoteEarly adult4.54x10-12 
preweaning lethality, incomplete penetrance1 supporting datasetEpb41tm1b(KOMP)MbphomozygoteEarly adultN/A * 
decreased mean corpuscular hemoglobin1 supporting datasetEpb41tm1b(KOMP)MbpheterozygoteEarly adult8.26x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Epb41tm1a(KOMP)MbpKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Epb41tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Epb41tm1b(KOMP)MbpReporter-tagged deletion allele (with selection cassette)mouse
Epb41tm1e(KOMP)MbpTargeted, non-conditional alleleES Cell
Epb41tm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell

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