Eif4b | eukaryotic translation initiation factor 4B
Physiological systems
20 / 24 physiological systems tested
7 Significantly impacted by the knock-out
Homeostasis/metabolism Embryo Growth/size/body region Hearing/vestibular/ear Behavior/neurological Cardiovascular system Mortality/aging
13 No significant impact
4 Not tested
Data collections
Gene metrics:8Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| preweaning lethality, complete penetrance | 1 supporting dataset | Eif4bem1(IMPC)J | homozygote | Early adult | N/A * | ||
| increased grip strength | 2 supporting datasets | Eif4bem1(IMPC)J | heterozygote | Early adult | 5.9x10-10 | ||
| embryonic growth retardation | 1 supporting dataset | Eif4bem1(IMPC)J | homozygote | E15.5 | N/A * | ||
| edema | 1 supporting dataset | Eif4bem1(IMPC)J | homozygote | E15.5 | N/A * | ||
| prolonged RR interval | 1 supporting dataset | Eif4bem1(IMPC)J | heterozygote | Early adult | 2.73x10-5 | ||
| hemorrhage | 1 supporting dataset | Eif4bem1(IMPC)J | homozygote | E15.5 | N/A * | ||
| abnormal locomotor behavior | 1 supporting dataset | Eif4bem1(IMPC)J | heterozygote | Early adult | 1.99x10-7 | ||
| abnormal auditory brainstem response | 2 supporting datasets | Eif4bem1(IMPC)J | heterozygote | Early adult | 1.6x10-5 |
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External links
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| Eif4bem1(IMPC)J | Exon Deletion | | mouse |