Egfr | epidermal growth factor receptor

GeneMGI:95294Synonyms: avian erythroblastic leukemia viral (v-erb-b) oncogene homolog, Wa5, +3 more

Physiological systems

12 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Immune system Hematopoietic system

10 No significant impact

12 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:1Significant phenotypes

5Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



decreased leukocyte cell number	1 supporting dataset		Egfr^{tm1a(EUCOMM)Wtsi}	heterozygote	Early adult		4.77x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Egfr.

Associated images

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Histopathology

There is no histopathology data found for Egfr.

IMPC related publications

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External links

No external links available for Egfr.

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*Egfr^{tm1(NCOM)Mfgc}*	Reporter-tagged deletion allele (with selection cassette)	‌	targeting vector es cell
*Egfr^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Egfr^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	es cell
*Egfr^{tm224(L1L2_gt1)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector
*Egfr^{tm224(L1L2_st1)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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