Serping1 | serine (or cysteine) peptidase inhibitor, clade G, member 1

GeneMGI:894696Synonyms: C1INH, C1 inhibitor, +1 more

Physiological systems

20 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Homeostasis/metabolism Nervous system Vision/eye Renal/urinary system

16 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:7Significant phenotypes
4Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased brain size1 supporting datasetSerping1em1(IMPC)MbphomozygoteEarly adultN/A * 
small kidney2 supporting datasetsSerping1em1(IMPC)MbphomozygoteEarly adultN/A * 
abnormal vitreous body morphology1 supporting datasetSerping1em1(IMPC)MbphomozygoteEarly adult5.99x10-5 
decreased circulating alkaline phosphatase level1 supporting datasetSerping1em1(IMPC)MbphomozygoteEarly adult4.17x10-7 
cataract1 supporting datasetSerping1em1(IMPC)MbphomozygoteEarly adult6.35x10-5 
abnormal kidney morphology2 supporting datasetsSerping1em1(IMPC)MbphomozygoteEarly adultN/A * 
abnormal brain morphology1 supporting datasetSerping1em1(IMPC)MbphomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
Download data as:  










* This parameter was manually assessed for significance.
Download data as:  

lacZ Expression

Associated images

Loading...

Histopathology

IMPC related publications

Loading...

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.

Serping1em1(IMPC)MbpExon Deletionmouse
Serping1tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
Serping1tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Serping1tm1e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell

The IMPC Newsletter

Get highlights of the most important data releases, news and events, delivered straight to your email inbox

Subscribe to newsletter