Nrsn1 | neurensin 1

GeneMGI:894662Synonyms: Neuro-p24, Vmp, +1 more

Physiological systems

18 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Homeostasis/metabolism Nervous system Behavior/neurological

15 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:6Significant phenotypes

0Associated diseases

Expression examined in:48Adult tissues

46Embryo tissues

Phenotypes

Phy. System:



decreased prepulse inhibition	1 supporting dataset	Nrsn1^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	3x10^-10
increased fasting circulating glucose level	1 supporting dataset	Nrsn1^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	4.86x10^-6
decreased thigmotaxis	2 supporting datasets	Nrsn1^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	7.13x10^-7
hyperactivity	1 supporting dataset	Nrsn1^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	7.59x10^-7
decreased exploration in new environment	1 supporting dataset	Nrsn1^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	6.77x10^-5
abnormal behavior	1 supporting dataset	Nrsn1^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	7.14x10^-7

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Nrsn1.

Associated images

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Histopathology

There is no histopathology data found for Nrsn1.

IMPC related publications

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External links

No external links available for Nrsn1.

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*Nrsn1^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell mouse
*Nrsn1^{tm1.1(KOMP)Vlcg}*	Reporter-tagged deletion allele (post Cre, with no selection cassette)	‌	mouse
*Nrsn1^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Nrsn1^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell
*Nrsn1^{tm2a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Nrsn1^{tm2e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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