Npm3 | nucleoplasmin 3

GeneMGI:894653Synonyms: Nub1

Physiological systems

18 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Homeostasis/metabolism Vision/eye Behavior/neurological

15 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

0Associated diseases

Expression examined in:48Adult tissues

50Embryo tissues

Phenotypes

Phy. System:



abnormal lens morphology	1 supporting dataset	Npm3^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	4.26x10^-5
abnormal sleep behavior	1 supporting dataset	Npm3^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	7.26x10^-5
decreased circulating glucose level	1 supporting dataset	Npm3^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	7.47x10^-7

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Npm3.

Associated images

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Histopathology

There is no histopathology data found for Npm3.

IMPC related publications

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External links

No external links available for Npm3.

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*Npm3^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell mouse
*Npm3^{tm1(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	targeting vector ES Cell
*Npm3^{tm1.1(KOMP)Vlcg}*	Reporter-tagged deletion allele (post Cre, with no selection cassette)	‌	mouse
*Npm3^{tm448970(Ifitm2_intron_L1L2_GT0_LF2A_LacZ_BetactP_neo)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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