Ppfibp2 | PTPRF interacting protein, binding protein 2 (liprin beta 2)

GeneMGI:894649Synonyms: liprin beta 2, Cclp1

Physiological systems

20 / 24 physiological systems tested

9 Significantly impacted by the knock-out

Reproductive system Immune system Integument Endocrine/exocrine gland Growth/size/body region Digestive/alimentary Vision/eye Behavior/neurological Renal/urinary system

11 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:10Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:

Life Stage:



enlarged urinary bladder	1 supporting dataset	Ppfibp2^em1(IMPC)Tcp	homozygote	Late adult	N/A ^*
abnormal seminal vesicle morphology	1 supporting dataset	Ppfibp2^em1(IMPC)Tcp	homozygote	Late adult	N/A ^*
abnormal stomach morphology	1 supporting dataset	Ppfibp2^em1(IMPC)Tcp	homozygote	Late adult	N/A ^*
abnormal vocalization	1 supporting dataset	Ppfibp2^em1(IMPC)Tcp	homozygote	Late adult	2.44x10^-7
thick skin	1 supporting dataset	Ppfibp2^em1(IMPC)Tcp	homozygote	Late adult	N/A ^*
enlarged lymph nodes	1 supporting dataset	Ppfibp2^em1(IMPC)Tcp	homozygote	Late adult	N/A ^*
enlarged lymph nodes	1 supporting dataset	Ppfibp2^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*
decreased grip strength	2 supporting datasets	Ppfibp2^em1(IMPC)Tcp	homozygote	Middle aged adult	3.74x10^-5
abnormal lens morphology	1 supporting dataset	Ppfibp2^em1(IMPC)Tcp	homozygote	Late adult	9.96x10^-6
decreased grip strength	2 supporting datasets	Ppfibp2^em1(IMPC)Tcp	homozygote	Late adult	4.83x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Ppfibp2.

Associated images

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Histopathology

There is no histopathology data found for Ppfibp2.

IMPC related publications

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External links

No external links available for Ppfibp2.

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*Ppfibp2^em1(IMPC)Tcp*	Exon Deletion	‌	mouse
*Ppfibp2^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell
*Ppfibp2^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Ppfibp2^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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