Sfrp1 | secreted frizzled-related protein 1

GeneMGI:892014Synonyms: sFRP-1, 2210415K03Rik

Physiological systems

20 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Adipose tissue Vision/eye

18 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Viability data
Body weight measurements
Embryo imaging data
Gene metrics:3Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal pupil morphology1 supporting datasetSfrp1tm1AkshhomozygoteEarly adult1.45x10-5 
increased total body fat amount1 supporting datasetSfrp1tm1AkshhomozygoteEarly adult5.6x10-5 
abnormal iris morphology1 supporting datasetSfrp1tm1AkshhomozygoteEarly adult4.01x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Sfrp1tm1(EGFP/cre/ERT2)WtsiReporter-tagged deletion allele (with selection cassette)ES Cell
mouse
Sfrp1tm1.1(EGFP_CreERT2)WtsiReporter-tagged deletion allele (post Cre, with no selection cassette)ES Cell
Sfrp1tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Sfrp1tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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