Cps1 | carbamoyl-phosphate synthetase 1
Physiological systems
17 / 24 physiological systems tested
5 Significantly impacted by the knock-out
Homeostasis/metabolism Immune system Hematopoietic system Behavior/neurological Mortality/aging
12 No significant impact
7 Not tested
Data collections
Gene metrics:8Significant phenotypes
3Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| increased lymphocyte cell number | 1 supporting dataset | Cps1em1(IMPC)H | heterozygote | Early adult | 3.54x10-8 | ||
| preweaning lethality, complete penetrance | 1 supporting dataset | Cps1em1(IMPC)H | homozygote | Early adult | N/A * | ||
| increased grip strength | 1 supporting dataset | Cps1em1(IMPC)H | heterozygote | Early adult | 6.9x10-5 | ||
| thrombocytosis | 1 supporting dataset | Cps1em1(IMPC)H | heterozygote | Early adult | 3.79x10-5 | ||
| decreased neutrophil cell number | 2 supporting datasets | Cps1em1(IMPC)H | heterozygote | Early adult | 1.7x10-5 | ||
| increased circulating cholesterol level | 1 supporting dataset | Cps1em1(IMPC)H | heterozygote | Early adult | 7.22x10-5 | ||
| increased circulating HDL cholesterol level | 1 supporting dataset | Cps1em1(IMPC)H | heterozygote | Early adult | 3.41x10-5 | ||
| decreased circulating potassium level | 1 supporting dataset | Cps1em1(IMPC)H | heterozygote | Early adult | 8.78x10-6 |
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External links
No external links available for Cps1.
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| Cps1em1(IMPC)H | Exon Deletion | | mouse |
| Cps1em2(IMPC)H | Exon Deletion | | mouse |
| Cps1tm239751(L1L2_Bact_P) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |