Cyp21a1 | cytochrome P450, family 21, subfamily a, polypeptide 1
Physiological systems
20 / 24 physiological systems tested
6 Significantly impacted by the knock-out
Immune system Integument Growth/size/body region Hematopoietic system Behavior/neurological Mortality/aging
14 No significant impact
4 Not tested
Data collections
Gene metrics:7Significant phenotypes
3Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| enlarged spleen | 1 supporting dataset | Cyp21a1em1(IMPC)Tcp | heterozygote | Early adult | N/A * | ||
| preweaning lethality, complete penetrance | 1 supporting dataset | Cyp21a1em1(IMPC)Tcp | homozygote | Early adult | N/A * | ||
| preweaning lethality, incomplete penetrance | 2 supporting datasets | Cyp21a1em1(IMPC)Tcp | homozygote | Early adult | N/A * | ||
| pallor | 1 supporting dataset | Cyp21a1em1(IMPC)Tcp | homozygote | E18.5 | N/A * | ||
| enhanced contextual conditioning behavior | 1 supporting dataset | Cyp21a1em1(IMPC)Tcp | heterozygote | Early adult | 9.96x10-5 | ||
| abnormal skin morphology | 2 supporting datasets | Cyp21a1em1(IMPC)Tcp | heterozygote | Early adult | N/A * | ||
| decreased exploration in new environment | 2 supporting datasets | Cyp21a1em1(IMPC)Tcp | heterozygote | Early adult | 3.21x10-7 |
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External links
No external links available for Cyp21a1.
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| Cyp21a1em1(IMPC)Tcp | Exon Deletion | | mouse |