Cyp19a1 | cytochrome P450, family 19, subfamily a, polypeptide 1

GeneMGI:88587Synonyms: Ar, Int-5, +5 more

Physiological systems

19 / 24 physiological systems tested

6 Significantly impacted by the knock-out

Homeostasis/metabolism Immune system Adipose tissue Growth/size/body region Hematopoietic system Behavior/neurological

13 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:19Significant phenotypes

4Associated diseases

Expression examined in:46Adult tissues

0Embryo tissues

Phenotypes

Phy. System:

Life Stage:



abnormal gait	1 supporting dataset	Cyp19a1^{tm1b(EUCOMM)Hmgu}	homozygote	Late adult	5.44x10^-5
increased circulating serum albumin level	1 supporting dataset	Cyp19a1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	7.79x10^-9
decreased locomotor activity	5 supporting datasets	Cyp19a1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	4.33x10^-5
thrombocytosis	1 supporting dataset	Cyp19a1^{tm1b(EUCOMM)Hmgu}	homozygote	Late adult	5.91x10^-10
increased neutrophil cell number	2 supporting datasets	Cyp19a1^{tm1b(EUCOMM)Hmgu}	homozygote	Late adult	1.28x10^-6
decreased locomotor activity	8 supporting datasets	Cyp19a1^{tm1b(EUCOMM)Hmgu}	homozygote	Late adult	9.1x10^-15
increased fasting circulating glucose level	1 supporting dataset	Cyp19a1^{tm1b(EUCOMM)Hmgu}	homozygote	Late adult	3.67x10^-6
increased total body fat amount	2 supporting datasets	Cyp19a1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	5.61x10^-6
decreased mean corpuscular hemoglobin concentration	1 supporting dataset	Cyp19a1^{tm1b(EUCOMM)Hmgu}	homozygote	Late adult	6.27x10^-5
tremors	1 supporting dataset	Cyp19a1^{tm1b(EUCOMM)Hmgu}	homozygote	Late adult	7.32x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

Download data as:

Rows per page:

‌



‌	‌	‌	‌	‌	‌	‌	‌	‌	‌

* This parameter was manually assessed for significance.

Download data as:

lacZ Expression

No adult expression data available for Cyp19a1.

Associated images

Loading...

Histopathology

There is no histopathology data found for Cyp19a1.

IMPC related publications

Loading...

External links

No external links available for Cyp19a1.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.



*Cyp19a1^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Cyp19a1^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Cyp19a1^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

My Genes