Masp1 | MBL associated serine protease 1

GeneMGI:88492Synonyms: Crarf

Physiological systems

18 / 24 physiological systems tested

6 Significantly impacted by the knock-out

Homeostasis/metabolism Growth/size/body region Vision/eye Behavior/neurological Cardiovascular system Mortality/aging

12 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:9Significant phenotypes

2Associated diseases

Expression examined in:50Adult tissues

52Embryo tissues

Phenotypes

Phy. System:



decreased heart rate	1 supporting dataset	Masp1^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	6.78x10^-5
hyperactivity	3 supporting datasets	Masp1^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	6.72x10^-6
increased circulating alkaline phosphatase level	1 supporting dataset	Masp1^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	1.46x10^-10
prolonged RR interval	1 supporting dataset	Masp1^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	4.71x10^-5
decreased fasting circulating glucose level	1 supporting dataset	Masp1^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	2.05x10^-9
increased circulating sodium level	1 supporting dataset	Masp1^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	3.83x10^-6
irregularly shaped pupil	1 supporting dataset	Masp1^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	1.66x10^-5
preweaning lethality, incomplete penetrance	1 supporting dataset	Masp1^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	N/A ^*
decreased body length	1 supporting dataset	Masp1^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	7.99x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Masp1.

Associated images

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Histopathology

There is no histopathology data found for Masp1.

IMPC related publications

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External links

No external links available for Masp1.

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*Masp1^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell mouse
*Masp1^{tm1.1(KOMP)Vlcg}*	Reporter-tagged deletion allele (post Cre, with no selection cassette)	‌	mouse
*Masp1^{tm277832(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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