Cox5b | cytochrome c oxidase subunit 5B

GeneMGI:88475

Physiological systems

21 / 24 physiological systems tested

6 Significantly impacted by the knock-out

Integument Limbs/digits/tail Vision/eye Liver/biliary system Behavior/neurological Mortality/aging

15 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:9Significant phenotypes

0Associated diseases

Expression examined in:51Adult tissues

62Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



abnormal skin coloration	1 supporting dataset	Cox5b^{tm2b(EUCOMM)Hmgu}	heterozygote	Early adult	8.89x10^-7
unresponsive to tactile stimuli	1 supporting dataset	Cox5b^{tm2b(EUCOMM)Hmgu}	heterozygote	E18.5	N/A ^*
abnormal liver size	1 supporting dataset	Cox5b^{tm2b(EUCOMM)Hmgu}	homozygote	E12.5	N/A ^*
pallor	1 supporting dataset	Cox5b^{tm2b(EUCOMM)Hmgu}	homozygote	E12.5	N/A ^*
abnormal embryonic autopod plate morphology	1 supporting dataset	Cox5b^{tm2b(EUCOMM)Hmgu}	homozygote	E12.5	N/A ^*
persistence of hyaloid vascular system	1 supporting dataset	Cox5b^{tm2b(EUCOMM)Hmgu}	heterozygote	Early adult	4.02x10^-5
preweaning lethality, complete penetrance	3 supporting datasets	Cox5b^{tm2b(EUCOMM)Hmgu}	homozygote	Early adult	N/A ^*
prenatal lethality prior to heart atrial septation	1 supporting dataset	Cox5b^{tm2b(EUCOMM)Hmgu}	homozygote	E15.5	N/A ^*
pale liver	1 supporting dataset	Cox5b^{tm2b(EUCOMM)Hmgu}	homozygote	E12.5	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

Download data as:

‌



‌	‌	‌	‌	‌	‌	‌	‌	‌	‌

* This parameter was manually assessed for significance.

Download data as:

lacZ Expression

No adult expression data available for Cox5b.

Associated images

Loading...

Histopathology

There is no histopathology data found for Cox5b.

IMPC related publications

Loading...

External links

No external links available for Cox5b.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.



*Cox5b^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	es cell
*Cox5b^{tm2a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Cox5b^{tm2b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Cox5b^{tm2e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	es cell

My Genes