Col9a2 | collagen, type IX, alpha 2

GeneMGI:88466Synonyms: Col9a-2

Physiological systems

19 / 24 physiological systems tested

6 Significantly impacted by the knock-out

Homeostasis/metabolism Limbs/digits/tail Hearing/vestibular/ear Nervous system Behavior/neurological Skeleton

13 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:15Significant phenotypes

4Associated diseases

Expression examined in:46Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



abnormal femur morphology	1 supporting dataset	Col9a2^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	2.51x10^-14
increased circulating alkaline phosphatase level	1 supporting dataset	Col9a2^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	4.83x10^-5
decreased prepulse inhibition	2 supporting datasets	Col9a2^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	5.44x10^-9
tremors	1 supporting dataset	Col9a2^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	1.21x10^-6
abnormal humerus morphology	1 supporting dataset	Col9a2^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	2.61x10^-14
abnormal ulna morphology	1 supporting dataset	Col9a2^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	2.57x10^-14
short tibia	1 supporting dataset	Col9a2^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	2.54x10^-10
abnormal joint morphology	1 supporting dataset	Col9a2^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	2.61x10^-14
abnormal auditory brainstem response	5 supporting datasets	Col9a2^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	9.63x10^-7
abnormal pelvic girdle bone morphology	1 supporting dataset	Col9a2^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	5.95x10^-8

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Col9a2.

Associated images

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Histopathology

There is no histopathology data found for Col9a2.

IMPC related publications

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External links

No external links available for Col9a2.

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*Col9a2^{tm1(NCOM)Cmhd}*	Reporter-tagged deletion allele (with selection cassette)	‌	targeting vector ES Cell
*Col9a2^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Col9a2^{tm1b(EUCOMM)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Col9a2^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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